Vitamin E is associated with reduced immune function and severity of the infection. Vitamin C deficiency results in bactericidal activity of phagocytes deficiency reduces lymphocyte response to mitogens decreased production of IL-2 altered the differentiation of T cells in thymus and increased myocardial injury during viral infection. The vitamin E during viral or bacterial infections (influenza, murine AIDS, the herpes simplex virus, Staphylococcus aureus, parainfluenza, Clostridium pelfringens a) reduce mortality or the severity of infection in different animal models.
However, all studies show a better resistance to infection vitamin E 85 have been found, and are not aware of any studies in humans have tested this theory that in humans and then to evaluate the impact and / or severity.
It is less clear whether vitamin E above the RDA increased resistance to infections in healthy people. The most promising results from studies with the elderly. In several randomized controlled trials, the responses were different doses of vitamin E for the elderly for various periods and granted refuge measured. Two studies of supplements administered (100-800 mg / day) for at least 6 months extension of several parameters), including immune dihydrotestosterone (reaction DTH, mitogen-induced IL-2 production and increase the share of antibodies against tetanus vaccine hepatitis B, and found one of these studies, the best results in patients receiving 200 mg / day of vitamin E, but more vitamin E (800 mg / day) did not further improve the immune response.
Study results did not improve the immune response in the elderly can consume 100 mg / day. But in this study, subjects received the award for only 3 months, maybe longer supplementation is necessary to observe an effect. The results of two other studies showed improvement in various aspects of the immune system (LPS-induced production of IL-1, TNFa, mitogen-induced lymphocyte proliferation) phagocytosis of neutrophils, when vitamin C (1 g / day) and vitamin E (200 -- 400 mg / day) were administered to healthy young adults and elderly. The mechanisms that may affect the absorption of vitamin E, immune response, have not yet determined.
At this point, the results for vitamin E and immunity in the elderly is promising. However, other large randomized controlled trials are needed before it is possible to determine whether vitamin E resulted in lower susceptibility to infection.
However, it was considered that this effect was associated with vitamin C, like vitamin E, because the post-race symptoms of URI reduction is less than vitamin C Vitamin C + C alone. To our knowledge, are not aware of any studies that have examined possible links between vitamin E alone and the immune response is to enjoy exercise. Sort;-Haps this research may give some hope among the elderly.